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Ph.D in veterinary science, M.sc in applied microbiology, scientist, microbiologist, microbial biofilm researcher. Currently performing my post-doctoral research at University of California Santa Cruz, focusing on survival strategies of Helicobacter pylori, with a particular focus on biofilm and genes associated with this mode of growth.
Univeristy of California, Santa Cruz
Since November 2016
- Investigating Helicobacter pylori biofilm formation and its potential role in pathogenesis in the lab of Dr. Karen Ottemann. I'm using transcriptomic and genetic approaches to identify genes associated with H. pylori biofilm growth. We also use mouse-models for H. pylori infections and imaging approaches (CSLM and SEM) to characterize the biofilm structure its components.
1. Metabolic changes associated with Helicobacter pylori biofilm. S. Hathroubi, J. Zerebinski and K. M Ottemann (in preparation for npj Biofilms and Microbiomes)
2. Helicobacter pylori biofilm involves a multi-gene stress-biased response, including a structural role for flagella. S. Hathroubi, J. Zerebinski and K. M Ottemann. 2018. mBio, doi: https://doi.org/10.1101/412239.
3. Helicobacter pylori biofilm formation and its potential role in pathogenesis. S. Hathroubi, S. L. Servetas, I. Windham, D. S. Merrell, K. M Ottemann. 2018. Microbiology and Molecular Biology Reviews. (published, doi: 10.1128/MMBR.00001-18)
Since May 2018
- Guest lecture Microbiology and pathogenesis for undergraduates and graduates: Biofilm, the social life of microorganisms. University of California, Santa Cruz (Winter-Spring session 2018)
- Microbiology and pathogenesis METX 119-02 online, summer session online classes: Biofilm, the social life of microorganisms. Univeristy of California, Santa Cruz (Summer 2018)
- Teaching course microbial pathogenesis 2 for Master’s degree, veterinary science: Surface polysaccharides and envelope (Part_1. Microbial envelope and Part_2. Surface polysaccharides). Université de Montréal (Fall session 2015)
- Laboratory demonstrator for Master’s degree, veterinary science students: Basic practical microbiology. Université de Montréal. (2012- 2015)
University of California, Santa Cruz
- Supervising undergrad student Yasmine E. (University of California, Santa Cruz) - since August 2018
- Supervising Ph.D student Aaron C. (University of California, Santa Cruz) - since October 2017
- Supervising undergrad student Julia Z. (University of California, Santa Cruz) - October 2017-September 2018
- Supervising summer student Tyler Dewitt (University of California, Santa Cruz) - June-July 2017
- Supervising student internship Sarah-Eve Fontaine-Gosselin (University of Montreal) Bachelor of Life Science, Sherbrooke University) - January-May 2014
- # Invited speaker to INRS-INSTITUT ARMAND-FRAPPIER October 2018. Helicobacter pylori biofilm and the unexpected role of flagella.
# PBSE Research Conference 2018, Felton, California, USA. Unexpected role played by flagella during biofilm formation.
# UC Biosafety officer meeting 2018, Santa Cruz, USA. New Insights into Helicobacter pylori biofilm.
# WCBP Annual conference, 2017, Asilomar, California, USA. Novel genes associated with Helicobacter pylori biofilm growth.
# CRIPA symposium, 2016, St-Hyacinthe, Québec, Canada. Actinobacillus pleuropneumoniae biofilms mitigate innate immune response.
# ASM Biofilm, 2015, Chicago, USA. Actinobacillus pleuropneumoniae biofilms induce lower response of porcine alveolar macrophages.
# CRIPA symposium, 2015, St-Hyacinthe, Québec, Canada. Effect of sub-inhibitory concentrations of penicillin G on Actinobacillus pleuropneumoniae biofilm formation.
# Phd in 180sec (3MTMC) 2014, Science on stage, Faculté de médecine vétérinaire, St-Hyacinthe, Québec Canada. Best presentation 3rd prize. Rôle du biofilm dans la pathogénicité d’Actinobacillus pleuropneumoniae.
# Congrès BiSP 2013, Université Laval, Québec, Canada. Rôle des polysaccharides de surface dans la formation du biofilm chez Actinobacillus pleuropneumoniae.
- # Referee/reviewer for Frontiers Microbiology
# Referee reviewer for Journal of Infection in Developing Countries
Groupe de recherche sur les maladies infectieuses du porc (GREMIP)
Since April 2011
- Site-directed mutagenesis (allelic exchange)
- Immunodetection of extracellular polymeric substance (EPS)
- EPS extraction (eDNA...)
- Biofilms culture in static and dynamic conditions
- Drip flow reactor
- Enzymatic treatments on biofilms
- Immunodot tests
- Macrophages in vivo Infection
- PBMC isolation
- Lipid A extractions and structure analysis
Centre National de Greffe de Moelle Osseuse, Faculté de médecine de Tunis
to June 2010
- Antibiotic susceptibility tests and serotyping assay of P. aeruginosa clincal strains
- Static biofilm formation and enzymatic treatments
- Curcumin and berberine chloride test on biofilm
- Biofilm genes identification
- Swarming et twitching motility
Institut de Biologie Moléculaire et Médecine, Université Libre de Bruxelles
to June 2009
- E. coli chromosomal toxin antitoxin systems identification by PCR
- Phylogenetic analyses
Université de Montréal
- Assist students and teachers in location of print and non-print resouces
- Check books and materials in and out to students and teachers using the computerized circulation system
- Monitor student use of the library
- Assist in maintaining the appearance of the library
Université de Montréal
Since September 2012
- Monitoring students during the writing of tests/exams