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Skander Hathroubi

Skander Hathroubi

Senior Research Scientist | R&D Microbiology | Biofilm Expert | Inventor | Author

Microbiology and pathogenesis
Antibiofilm treatments and preventions
Antimicrobial biomaterials development
Coatings and hydrogels development
skander-hathroubi
40 years old
Employed Open to opportunities
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Senior Research Scientist specializing in R&D microbiology, with a Ph.D. in veterinary science and deep expertise in biofilms. Currently leading the microbiology laboratory at SPARTHA Medical, where I develop antimicrobial coatings and hydrogels for medical devices. My research spans biofilm architecture, pathogenesis, and innovative treatment strategies. An inventor with multiple patents, I have also held research positions at Humboldt-Universität zu Berlin (Germany) and the University of California, Santa Cruz (USA). In addition to my scientific work, I am a writer and dedicated educator, actively contributing to the academic community through publications, teaching, and workshops.
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Experiences
  • Investigated Helicobacter pylori biofilm formation and its potential role in pathogenesis.
  • Employed transcriptomic and genetic approaches to identify genes involved in biofilm development.
  • Utilized mouse models of H. pylori infection to study in vivo biofilm behavior.
  • Applied confocal scanning laser microscopy (CSLM) and scanning electron microscopy (SEM) to characterize biofilm structure and composition.
  • Publications:
    1. Hathroubi S., Servetas S.L., Windham I., Merrell D.S., Ottemann K.M. (2018). Helicobacter pylori biofilm formation and its potential role in pathogenesis.
      Microbiology and Molecular Biology Reviews, 82(2): e00001 18
    2. Hathroubi S., Zerebinski J., Ottemann K.M. (2018). Helicobacter pylori Biofilm Involves a Multigene Stress Biased Response, Including a Structural Role for Flagella.
      mBio, 9(5): e01973 18.
    3. Hathroubi S., Hu S., Ottemann K.M. (2020). Genetic requirements and transcriptomics of Helicobacter pylori biofilm formation on abiotic and biotic surfaces. npj Biofilms and Microbiomes, 6(1): 56.
    4. Hathroubi S., Zerebinski J., Clarke A., Ottemann K.M. (2020). Helicobacter pylori Biofilm Confers Antibiotic Tolerance in Part via A Protein Dependent Mechanism.Antibiotics, 9(6): 355
    5. Tachiyama, S. T.; Peterson, B.; Khan, M. F.; Liu, X.; Hathroubi, S.; Liu, J.; Roujeinikova, A.; Ottemann, K. M. (2022). The flagellar motor protein FliL forms a scaffold of circumferentially aligned subunits that is essential for torque generation in Helicobacter pylori. Proceedings of the National Academy of Sciences, 119(4), e2118401119.
    6. Elshenawi, Y.; Hathroubi, S.; Hu, S.; Liu, X.; Ottemann, K. M. (2025). Genetic Basis of Gap Formation Between Migrating Helicobacter pylori Colonies in Soft Agar Assays. Microorganisms, 13(5), 1087. DOI:10.3390/microorganisms13051087